Author

Jianyun Zhang

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Sep 2026

A Pilot Clinical Trial of Cetuximab Combined With Tislelizumab as Neoadjuvant Therapy for Locally Advanced Oral Squamous Cell Carcinoma.

BACKGROUND Chemotherapy-free neoadjuvant strategies remain undefined for patients with locally advanced oral squamous cell carcinoma (OSCC) who are medically unsuitable for conventional cytotoxic chemotherapy. METHODS In this prospective single-arm pilot trial, 15 patients received two cycles of neoadjuvant tislelizu...

Wen-Jie Wu, Pu-Gen An, Xiao Hu et al. · Head and Neck · 0 citations

Open access Jul 2026

Spatially resolved proteomics provides insights into the normal-dysplasia-tumor continuum in oral squamous cell carcinoma.

Spatially resolved proteomics of archived formalin-fixed paraffin-embedded tissues provides a morphology-anchored proteomic continuum of oral malignant transformation in a small spatially matched cohort, suggesting that OSCC progression involves early-shift, progressive, and transient dysplasia-specific programs.

Chaoran Peng, Xinjia Cai, Ming-Wei Huang et al. · BMC Oral Health · 0 citations