Immunometabolic reprogramming in osteoporosis–osteoarthritis comorbidity: from inflammaging to osteochondral unit degeneration
Osteoporosis (OP) and osteoarthritis (OA) are common and highly co-occurring degenerative bone diseases in the elderly population, and their comorbidity mechanisms cannot be fully explained by traditional factors such as mechanical load, changes in bone mass, or hormonal imbalance. OP is primarily characterized by syst...