11-Oxo-mogroside V attenuates lung adenocarcinoma progression by disrupting metabolic homeostasis and suppressing TGFβ2/Myc-dependent oncogenic signaling.
BACKGROUND Lung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality worldwide, with nonsmokers comprising a notable proportion of cases. The complexity of its molecular pathogenesis poses substantial challenges for the development of effective therapeutic strategies. Traditional Chinese medicine-derive...