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Aug 2026

Loss of bves leads to cardiac contractile dysfunction and myocardial mitochondrial damage in zebrafish.

The Popeye domain-containing protein 1 (Popdc1, also known as Bves) is a transmembrane protein whose dysfunction is closely associated with various diseases. Clinical studies have identified that mutations in the bves gene predispose individuals to limb-girdle muscular dystrophy. However, a marked reduction in Bves pro...

Wanwan Cai, Wan-Bang Zhou, Jun-Rong Lei et al. · 0 citations
Review Open access Aug 2026

Engineered extracellular vesicles: pharmacological barriers, engineering strategies, and translational opportunities

Extracellular vesicle (EV) therapeutics are progressing from broad proof-of-concept studies toward product-specific engineering and clinically defined applications. Native EVs offer biological membrane functions and the capacity to transport diverse molecular cargoes, but their therapeutic performance is limited by low...

Jiao Xu, Zhi Li, Da Liu et al. · 0 citations

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