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Author

Jiaxin Gong

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Oct 2026

Safety of Autologous Infusion of CER T Cells in Nonhuman Primates.

Cellular immunotherapies have shown great promise in the treatment of various diseases. Chimeric engulfment receptor (CER)-engineered T cells were developed to utilize the extracellular T-cell immunoglobulin and mucin domain-containing 4 (TIM-4) domain and intracellular engulfment signaling domains to target and enhanc...

K. Eichholz, A. Okoye, B. Varco-Merth et al. · 0 citations
Jul 2026

EFO2 promotes triple-negative breast cancer progression and reduces CD8+ T cell-mediated killing by acetylating USF1 to enhance SLC2A1-mediated glycolysis.

A novel EFO2/USF1/SLC2A1 signaling axis that modulates glycolytic metabolism and CD8⁺T cell cytotoxicity is identified, positioning EFO2 as a promising therapeutic target for TNBC treatment.

Lin Jia, Liru Li, Junning Peng et al. · 0 citations

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