TTS-Design: Test-Time Compute Scaling for Structure-Guided Protein Design
TTS-Design is proposed, a test-time compute scaling framework that enhances protein sequence design without retraining models or relying on larger training datasets, and can consistently improve sequence recovery and structural reliability across different backbone models, without retraining or increasing model size.
Zizhe Jin, Yi Zheng, Huan Yee Koh et al.
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