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Jicun Chen

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Review Open access Aug 2026

Non-histone protein L-lactylation in cancer: a metabolic switch for immune evasion and therapeutic resistance

This work defines the spatially compartmentalized catalytic network governing this process, detailing how nuclear EP300/CBP, cytosolic AARS1, and mitochondrial AARS2 mediate stereospecific targeted modifications.

Ying-Ying Guo, Lanyang Gao, Shundan Li et al. · 0 citations

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