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Jie Chai

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Jul 2026

Circ_0027446: a novel biomarker and therapeutic target to combat colorectal cancer and enhance immune response

Higher circ_0027446 expression was associated with larger tumor size, lymph node metastasis, advanced TNM stage, and shorter overall survival, and may contribute to tumor progression and immune escape-related changes, at least partly through the miR-6882-3p/HOXB9 axis.

Qing-Ye Zhao, Chen Qin, Jie Chai et al. · 0 citations