Author

Jie-Feng He

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Open access Aug 2026

ZMIZ1 promotes aerobic glycolysis and development of hepatocellular carcinoma through inducing NOTCH1-mediated transcription of PYCR1

Hepatocellular carcinoma (HCC) is characterized by profound metabolic reprogramming that promotes tumor progression. Although zinc finger MIZ-type containing 1 (ZMIZ1) has been implicated in several malignancies, its biological function and underlying mechanism in HCC remain unclear. The expression and clinical signifi...

Jie-Feng He, Chao Zhang, Guo Chen et al. · Journal of Translational Med... · 0 citations

Open access Jan 2026

Loganin Ameliorates Cholestatic Liver Fibrosis by Inhibiting Hepatic Stellate Cell Autophagy and Activation Through EGFR Signaling

Liver cirrhosis represents the irreversible end‐stage of various chronic liver diseases, whereas hepatic fibrosis, characterized by hepatic stellate cell (HSC) activation, constitutes the critical pathological intermediate in this progression. In this study, we investigated the antifibrotic effects of loganin, a natura...

Xinwen Li, Hui-Ling Zhang, Chao Zhang et al. · Mediators of Inflammation · 0 citations