Objective This study aimed to investigate the therapeutic effects of Pharbitis nil polysaccharides (PNP) on ulcerative colitis (UC) and elucidate the underlying mechanisms. Methods PNP were extracted using water extraction and alcohol precipitation. Acute UC was induced in mice by administration of 3% dextran sulfate s...
Jie Hu, Dan Wu, Ming-Zhu Wu et al.· Natural Product Communicatio...· 0 citations
Crohn’s disease (CD) is a chronic, relapsing inflammatory disorder of the gastrointestinal tract with an unclear etiology. Current Western therapies, including 5-aminosalicylates, corticosteroids, biologics, and immunomodulators, often fail to maintain sustained remission and are associated with significant adverse eff...
Meng'en Zhou, Yan Chen, Jie Hu et al.· Frontiers in Immunology· 0 citations
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