Jie Jia

Single‐Cell Analysis of Hepatic Non‐Parenchymal Cells Reveals Endothelial Dysfunction and Altered Endothelial and B Cell Communication in Acute‐on‐Chronic Liver Failure

Acute‐on‐chronic liver failure (ACLF) is a fatal syndrome defined by hepatic decompensation and systemic inflammation, yet the underlying cellular networks remain elusive. Here, we established an ACLF mouse model recapitulating clinical hallmarks and performed single‐cell RNA sequencing (scRNA‐seq) on hepatic non‐paren...