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Open access Oct 2026

CXCR4-Functionalized Biomimetic Nanoparticles Enable ROS-Triggered Hesperetin Release for Acute Lung Injury Therapy

Objective Acute lung injury (ALI) features uncontrolled pulmonary inflammation and excessive reactive oxygen species (ROS), lacking effective targeted therapies. Hesperetin (HST) has anti-inflammatory and antioxidant effects, but poor solubility and weak lesion targeting limit its application. Herein, based on the char...

Jie Li, Wen-Bo Zhao, Liang-Liang Xue et al. · 0 citations
Open access Aug 2026

Biomimetic PD-1-MSCs membrane-engineered nanoparticles for enhanced blood-brain barrier penetration and anti- glioma therapy

Objective Glioma is the most common and aggressive primary intracranial tumor. Its clinical management is substantially hindered by the blood–brain barrier (BBB) and the immunosuppressive tumor microenvironment (TME). This study aimed to construct PD-1-functionalized mesenchymal stem cell (MSC) membrane biomimetic nano...

Jie Li, Yuhao Gao, Wen-Bo Zhao et al. · 0 citations

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