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Author

Jie Li

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Sep 2026

Development and Preclinical Evaluation of [68Ga]Ga-DOTA-L3: A Novel PET Tracer for Quantitative Imaging of Carbonic Anhydrase IX

Carbonic anhydrase IX (CA IX) is a key biomarker for tumor hypoxia and a promising target for molecular imaging. In this study, we developed [68Ga]Ga-DOTA-L3, a novel small-molecule CA IX-targeted PET tracer. The radiolabeling was optimized to consistently achieve a radiochemical purity of >98% (10 μg precursor, 90 °...

Jie Li, Yu-Hui Luo, Cheng-Yu Luo et al. · 0 citations
Jul 2026

Assembly mechanism-instructed precision nanocarriers: Esox lucius apoferritin for hydrophilic or hydrophobic drug loading and smart release.

It is demonstrated that apo-Fn undergoes controlled disassembly under mild acidic conditions, and efficiently reassembles upon neutralization or urea removal, and efficiently reassembles upon neutralization or urea removal.

Jiaoqian Shang, Jie Li, Yabo Wei et al. · 0 citations

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