ESAT-6-derived lipopeptide-based mucosal vaccine elicits distinct humoral immune responses concomitant with a reduction in mycobacterium infection
These findings revealed that incorporating HKCC significantly increased cellular responses and mucosal IgA and systemic IgG titres in pre- and post-exposure models, respectively, and correlated with reduced mycobacterial burden in the lungs, spleens, and livers and with improved lung pathology.