Integrating Proteomics and Mendelian Randomization to Evaluate HGF as a Potential Mediator of Stroke Risk Factors.
PURPOSE Stroke prediction remains suboptimal. We aimed to identify plasma proteins associated with stroke risk and evaluate their potential as clinical biomarkers and causal mediators. EXPERIMENTAL DESIGN We used a multitiered proteomic approach in the UK Biobank (UKB). In a matched nested case-control study (672 cas...