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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jie Yao

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2 papers indexed here

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Open access Aug 2026

Plasma metabolomic signatures enable the diagnosis and prognosis of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a progressive heterogeneous lung disease driving global illness and death, yet reliable biomarkers for its early diagnosis, molecular subtyping and prognosis are lacking. Here, we conduct targeted plasma metabolomic profiling in two independent, deeply phenotyped cohorts...

Chen Li, Jie Yao, Fan Wu et al. · 0 citations
Aug 2026

Lactate derived from CAFs mediates H3K18la in stemness gene promoters, which promotes tumor malignant phenotype formation

It is demonstrated that lactate derived from CAFs promotes the expression of stemness genes by mediating H3K18 lactylation in the promoters of these genes in NSCLC cells, thereby accelerating the malignant phenotype formation of NSCLC cells.

Jie Yao, Guang-Bing Li, Ke Chen et al. · 0 citations

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