Author

Jill S. Barnholtz-Sloan

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Open access Sep 2026

SNP rs2853669 potentially elevates the risk of glioblastoma development and leads to worse prognosis when in cis with mutant TERT promoter in a Japanese cohort.

BACKGROUND Mutations in the telomerase reverse transcriptase (TERT) promoter region (TPM), particularly C228T and C250T, are common in IDH-wildtype glioblastoma (GBM). The single nucleotide polymorphism (SNP) rs2853669, also located in the TERT promoter, may influence telomerase activity, though its clinical relevance...

Daisuke Kawauchi, Yohei Miyake, B. Taylor et al. · Neuro-Oncology · 0 citations

Open access Aug 2026

Foundation model-enhanced multimodal survival prediction in glioblastoma across multi-institutional cohorts

MRI foundation models (FMs) have shown potential for improving performance of neuroimaging tasks, but their value specifically in Glioblastoma overall survival risk prediction remains unclear. In this study, we explored foundation model initialization for preoperative risk prediction using publicly available structur...

Rakesh Khanna, Fanyang Yu, Minkyu Park et al. · npj Precision Oncology · 0 citations