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Author

Jilu Zhang

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2 papers indexed here

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Open access Sep 2026

The IL-9R/Arg1 pathway promotes polyamine metabolism in human airway macrophages

Background: Lung macrophages are central regulators of inflammatory responses in the airways and lung parenchyma. Macrophages function as conduits for cytokine function in the inflammatory milieu. We previously demonstrated that IL-9-responsive macrophages are essential for allergic lung inflammation in an arginase 1 (...

Wen-Wu Zhang, I. Cheon, Abigail Pajulas et al. · 0 citations
Open access Jul 2026

Interleukin-9 Receptor Signaling Promotes an Immunosuppressive Tumor Immune Microenvironment in Oncogene-Driven Non-Small Cell Lung Cancer 2264775

Non-small cell lung cancer (NSCLC), particularly oncogene-driven subtypes, remains a leading cause of cancer-related mortality, underscoring the urgent need for novel immunotherapies that effectively target the tumor immune microenvironment (TIME). The interleukin-9 receptor (IL-9R) signaling pathway is understud...

Jilu Zhang, M. Kaplan · 0 citations

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