Author

Jinchao Zhang

3 papers indexed here

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Aug 2026

Cluster of Differentiation 36-Engineered Photosynthetic Cyanobacteria Enable Immunometabolic Reprogramming in Triple-Negative Breast Cancer.

Triple-negative breast cancer (TNBC) exhibits profound resistance to immunotherapy, largely due to a tumor microenvironment constrained by dysregulated lipid metabolism and persistent hypoxia. Excessive fatty acid uptake mediated by the scavenger receptor CD36 (Cluster of differentiation 36) imposes metabolic stress on...

Yuanhang Li, Zhengxin Yu, Ying Yang et al. · Acta Biomaterialia · 0 citations

Open access Jul 2026

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

ABSTRACT Diabetic wound healing is critically impaired by a pathological microenvironment with two core barriers: circulatory deficits from microangiopathy, and a loss of nanoscale topographical guidance due to extracellular matrix (ECM) disruption. To address this, we developed Musc@CP, an advanced dressing that syner...

Xiang Zheng, Mingmei Li, Jian-Jun Jiang et al. · Advancement of science · 0 citations

Open access Jul 2026

A novel pH-responsive nanoreactor for pyroptosis induction: multifaceted ROS amplification drives potent immunotherapy against triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is associated with rapid progression and poor sensitivity to monotherapies, necessitating combination strategies to enhance tumor immunogenicity, reprogram the tumor microenvironment (TME), and convert immunologically "cold" tumors into "hot" ones. In this study, we develop a pH-res...

Wenjia Liu, Ying Wang, Xiangyu Hao et al. · Journal of Nanobiotechnology · 0 citations