Open access
Aug 2026
Clinical validation of KIF11 overexpression in colorectal cancer and its potential association with the antitumor effects of nitidine chloride
In vitro and limited xenograft data indicate that NC restrains CRC growth chiefly through the RAD21–KIF11 axis; KIF11 represents a promising preclinical target, though comprehensive systematic in vivo pharmacodynamic and translational animal validation remains absent in the current study and requires further independen...
Hui Li, Rui Lin, Ke-Jun Wu et al.
· Hereditas · 0 citations