Open access
Oct 2026
A circRNA-microRNA-Pdcd1 axis drives microglial activation and retinal ganglion cell degeneration
Retinal ganglion cell (RGC) degeneration is the primary cause of vision loss, driven by the complicated effects of intrinsic neuronal damage and neuroinflammation. However, current single-target therapies fail to address these dual pathological challenges. CircRNAs, functioning through ceRNA networks, represent a m...
Lan-Fang Sun, Xiao-Yu Ke, J.-J. Yu et al.
· Communications Biology · 0 citations