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Open access Aug 2026

Loss of wbp11 causes multi-system developmental defects: a zebrafish model of VACTERL association

Introduction VACTERL association is a congenital disorder characterized by the non-random co-occurrence of vertebral, anal, cardiac, tracheo-esophageal, renal, and limb anomalies. WBP11 has been identified as a candidate causative gene; however, existing heterozygous Wbp11 knockout mice recapitulate only a subset of th...

Yu Chen, Shiqi You, Ying-Shuo Zhang et al. · 0 citations
Review Open access Aug 2026

Emerging molecular mechanisms of the ECM–exosome growth-plate axis in idiopathic short stature

Overall, the proposed ECM–exosome growth-plate axis may help frame ISS as a potentially molecularly stratifiable disorder involving chondrocyte state-transition failure, rather than solely as an endocrine diagnosis of exclusion.

Li-Zhen Piao, Hong Wang, Qiu-Ying Zhang et al. · 0 citations

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