Author

Jin-Ning Song

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Open access Sep 2026

Targeting Nectin-4 sensitizes glioblastoma to temozolomide

Background Temozolomide (TMZ) remains the first-line chemotherapeutic agent for glioblastoma (GBM), but its clinical efficacy is often limited by acquired resistance. This study aimed to investigate whether nectin-4 could serve as a target to sensitize GBM cells to TMZ and to determine whether resveratrol enhances TMZ...

Xiao-Guang Zhang, Hua Wang, Jin-Ning Song · Frontiers in Pharmacology · 0 citations

Open access Sep 2026

Genetic Prioritization of Plasma Proteins Across Dementia Subtypes: A Proteome-Wide Mendelian Randomization and Bayesian Colocalization Analysis

Dementia is clinically and biologically heterogeneous, and genetically supported plasma protein associations across dementia subtypes remain incompletely characterized. We aimed to genetically prioritize plasma proteins associated with overall dementia and major dementia subtypes using proteome-wide Mendelian randomiza...

Xin-Yang Yan, Long-Xiao Zhang, Jia-Xi Li et al. · Cellular and molecular neuro... · 0 citations

Jul 2026

Integrating Large-Scale Bulk and Single-Cell RNA Sequencing with Machine Learning: Unveiling the Cytokine Landscape of Glioblastoma and Constructing a Prognostic Feature Model.

A highly reproducible and patient-specific prognostic prediction model based on a cytokine-related gene signature, combining several ML techniques and a large set of bioinformatic features that has the potential to be an effective and promising strategy for improving clinical outcomes in patients with GBM.

Long-Xiao Zhang, Xin-Yang Yan, Yunfei Zhou et al. · Current Cancer Drug Targets · 0 citations