Author

Jin-Peng Sun

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Open access Aug 2026

N-linked glycosylation of the EP3α receptor is essential for the regulation of platelet homeostasis

It is concluded that N-linked glycosylation of EP3α is critical for platelet regulation through modulation of PGE 2 /EP3α/G i -mediated cAMP and Ca 2+ signaling.

Yuhong Wang, Yi-Zhe Li, Junyan Wang et al. · Communications Biology · 0 citations

Open access Jul 2026

Conformational Basis of Functionally Selective Allosteric Modulation of the Angiotensin II type 1 Receptor by Small Molecules

The DNA- encoded library screening-guided isolation and pharmacological characterization of the first small molecule AT1R allosteric ligands are reported, uncovering new mechanisms for precisely controlling the dynamic behavior of the AT1R with implications for drug development targeting this pathophysiologically impor...

Samuel Liu, Peng Xiao, M. Elgeti et al. · bioRxiv · 0 citations