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Jinpeng Wu

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Review Open access Jul 2026

Spatial organization of the TNBC tumor microenvironment: multicellular niches, T-cell bottlenecks, and therapeutic opportunities.

How myeloid programs and neutrophil extracellular trap formation, cancer-associated fibroblast subsets and extracellular matrix barriers, aberrant vasculature and hypoxia-linked metabolism, and the tumor-nerve signaling axis cooperatively shape immunosuppressive niches that drive progression and therapeutic resistance is delineated.

Jin-Peng Wu, Jingjing Fan, Tong Sha et al. · Journal of Translational Med... · 0 citations