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Jin-San Zhang

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Aug 2026

Dual epithelial-mesenchymal induction of Sfrp1/Frzb constrains alveolar epithelial differentiation in neonatal hyperoxia-induced lung injury.

A fibroblast-dominated Sfrp1/Frzb-mediated niche is identified that constrains AT2 differentiation into AT1 cells, providing a cellular basis for impaired alveolar regeneration in BPD and suggesting potential therapeutic targets.

Ming Xu, Liyan Xiang, Gongxia Ling et al. · 0 citations

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