Review
Open access
Sep 2026
Posttranslational Modifications of p62/SQSTM1 in Health and Disease
ABSTRACT p62/SQSTM1 is a multifunctional adaptor protein that serves as a central hub integrating cellular stress responses, including selective autophagy, antioxidant defense, metabolism, and immune signaling. Its diverse functions are precisely orchestrated by a complex network of posttranslational modifications (PTM...
Wei-Kai Wang, Xin Jiang, Ru-Ning Qiu et al.
· MedComm · 0 citations