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Juvenile in vitro embryo transfer can shorten generation intervals, but its application in goats is constrained by the quantity-quality trade-off in oocytes from prepubertal donors. We established an age-specific workflow for Yudong black goats by separately optimizing ovarian superstimulation in juvenile and adult don...
Findings indicate that α-KG improves developmental competence and is associated with enhanced epigenetic remodeling in porcine SCNT embryos, at least in part through TET-associated pathways, providing a potential strategy for improving nuclear reprogramming efficiency in animal cloning.
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