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Jin-Xin Hu

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Sep 2026

Ultrafast 4-Azidopyridinium-Based Staudinger (UApS) Ligation for Bioorthogonal Labeling and Imaging.

An ultrafast 4-azidopyridinium-based Staudinger (UApS) ligation is reported that proceeds with large bimolecular reaction rate constants (103-104 M-1s-1) under catalyst-free, physiologically relevant conditions and should extend fast click chemical space, providing a new addition to the bioconjugation toolkit.

Xue-Kang Cai, Jie Zhang, Bai-Fan Wang et al. · 0 citations

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