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Author

Jing Dai

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2 papers indexed here

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Open access Sep 2026

A novel homozygous chromosomal deletion encompassing the ACTL9 gene is associated with cIVF polyspermy and male infertility.

Actin-like 9 (ACTL9) is a testis-specific actin-like protein located in the perinuclear theca of the sperm head and neck that plays a role in acrosome formation and sperm head shaping. Pathogenic mutations in ACTL9 have been reported to be associated with male infertility and fertilization failure after conventional in...

Xin-Yu Liu, Ya Yang, Zi-Li Li et al. · 0 citations
Open access Sep 2026

High sperm DNA fragmentation is associated with increased embryonic chromosomal abnormality: a retrospective study of 8 years involving 5637 couples undergoing ART

Does sperm DNA fragmentation impair blastocyst chromosomal integrity? A high sperm DNA fragmentation index (DFI) is associated with an increased risk of blastocyst aneuploidy, particularly when the man has poor semen quality or when the female partner is aged ≥35 years. Evidence linking sperm DFI to...

L. Lou, Peng-Cheng Xu, P. Xie et al. · 0 citations

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