Open access
Oct 2026
Joint associations of cardiovascular-kidney-metabolic syndrome and depressive symptoms with incident frailty: the mediating role of body roundness index
Frailty is a multidimensional geriatric syndrome associated with increased vulnerability to adverse outcomes in aging populations. Both cardiovascular-kidney-metabolic (CKM) syndrome and depressive symptoms have been independently linked to frailty, but their combined associations and underlying pathways remain u...
Shou-Chuang Zhang, Jia Tang, Chen Chen et al.
· Diabetology & Metabolic... · 0 citations