Review
Open access
Jul 2026
Urinary organophosphate metabolites, DNA methylation aging, and heart disease mortality in middle-aged and older adults: an exploratory cohort study with in vitro evidence of biological plausibility
Higher urinary DETP was associated with greater heart disease mortality in middle-aged and older adults, and in vitro experiments provided hypothesis-generating support—most directly for inflammatory signaling—rather than confirmation of the epidemiological pathway.
Yun-Li Song, Lihui Liang, Jing Hao et al.
· Frontiers in Public Health · 0 citations