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Author

Jing-Jing Jin

2 papers indexed here

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Open access Sep 2026

Improving the Accuracy of Papillary Thyroid Cancer Pathological Evaluation With Digital PCR Detection of the BRAF V600E Mutation

ABSTRACT Background The BRAF V600E mutation is an important diagnostic factor for papillary thyroid cancer (PTC). Digital PCR (dPCR) is a relatively new technology featured with extremely high sensitivity. This study aims to evaluate the performance of dPCR in detecting BRAF V600E mutations in PTC diagnosis. Methods A...

Na Yu, Kai Zhang, Ying Jiang et al. · 0 citations
Open access Sep 2026

Integrated stress response inhibition decouples cardiotoxicity from anthracycline chemotherapy while enhancing antitumor efficacy.

The clinical efficacy of anthracycline chemotherapeutics is severely limited by their dose-dependent cardiotoxicity, a condition lacking effective preventive strategies. We identify the maladaptive ATF4-dependent integrated stress response (ISR) program as a central driver of this pathology. In murine models, ISR inhib...

Si-Min Yang, Zheng-Yang Chen, Hong-Li Zhang et al. · 0 citations

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