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Author

Jing-Jing Luo

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Open access 2026

IL-23 promotes PD-L1 expression and tumor immune evasion via METTL16 pathway.

It is elucidated that IL-23 upregulates METTL16, which in turn enhances PD-L1 expression and facilitates tumor immune escape, which establishes the IL-23/METTL16/PD-L1 axis as a novel regulatory pathway and potential therapeutic target in cancer immunotherapy.

Xue-Shan Pan, Yue Wang, Jing-Jing Luo et al. · 1 citation

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