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Jing-Jing Pan

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Open access Sep 2026

Berberine attenuates diabetic kidney injury via FOXO1/SP1-associated regulation of renal SGLT-2 expression

Berberine (BBR), a plant-derived isoquinoline alkaloid, has been reported to exert anti-hyperglycemic and renoprotective effects. However, the mechanism by which BBR regulates renal glucose transport under diabetic conditions remains unclear. Sodium-glucose cotransporter-2 (SGLT-2), mainly expressed in renal proximal t...

Jing-Jing Pan, Xin-He Wang, Xin-Yuan Han et al. · 0 citations

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