Open access
Oct 2026
Tributyl phosphate induces liver aging via fumarate-mediated mitochondrial DNA escape triggered FPR2 activation.
BACKGROUND Liver aging-induced failure and dysfunction in other organs constitute a critical aging phenotype that is distinct from chronological aging. Unlike intrinsic aging, hepatic senescence is predominantly driven by environmental factors. Tributyl phosphate (TBP) was identified as a potential key environmental tr...
Li-Wei Yang, Hong-Hao Qian, Zhi-Li Ge et al.
· Ecotoxicology and Environmen... · 0 citations