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Author

Jing-Jing Sun

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Open access Aug 2026

Ion-Pair-Free Capillary HILIC-MS for Sensitive Nucleic Acid Analysis and RNA Modification Mapping

Mass spectrometry (MS)-based nucleic acid analysis provides direct chemical evidence for oligonucleotide sequence, composition, and modifications. However, oligonucleotide LC-MS analysis commonly relies on ion-pairing reversed-phase liquid chromatography (IP-RPLC). Although IP-RPLC provides strong retention and high-re...

Jun-Zhou Wu, Rana Togay, Jing-Jing Sun et al. · 0 citations
Open access Aug 2026

Quantitative RNA modification mapping by mass spectrometry with isobaric tags and nucleobase fragment analysis

The authors develop proteomics-style, RNA-specific isobaric tandem mass tags for quantitative RNA modification mapping by mass spectrometry, revealing condition-dependent changes and interdependencies among modification pathways.

Jun-Zhou Wu, Jing-Jing Sun, Yi-Feng Yuan et al. · 0 citations

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