Open access
Aug 2026
Sanguinarine chloride inducing ferroptosis and downregulating GPX4 expression in liver cancer: An integrated in silico, in vitro and in vivo study
Findings indicate that sanguinarine chloride exerts antitumor effects in liver cancer, at least in part, by inducing ferroptosis through GPX4 downregulation, supporting further investigation of SC as a potential therapeutic candidate.
Wenyi Ouyang, Jianxin Gao, Jing Liu et al.
· Experimental and Therapeutic... · 0 citations