Open access
Sep 2026
Isobavachalcone attenuates experimental periodontitis by suppressing PTGS2-associated macrophage ferroptosis and restoring periodontal immune homeostasis
Periodontitis (PD) is a destructive inflammatory disease driven by the collapse of immune homeostasis and alveolar bone resorption. Isobavachalcone (IBC) is a naturally occurring prenylated chalcone belonging to the plant flavonoid family, mainly enriched in the mature seeds of Cullen corylifolium , with report...
Ruo-Lan Yang, Yan-Ye Jin, Zi-Yi Wang et al.
· Frontiers in Pharmacology · 0 citations