Selaginella doederleinii–derived extracellular vesicle-like particles induce ferroptosis via the xCT/GPX4 axis and are associated with metabolic and gut microbiota alterations in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal malignancies worldwide, and the limited efficacy and adverse effects of current therapeutic strategies highlight the urgent need for safer and more effective anticancer approaches. Selaginella doederleinii, a traditional medicinal herb widely used i...