Author

Jing-Wen Qiu

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Aug 2026

Abnormal functional lateralization and cooperation in primary angle-closure glaucoma correlate with cell type-specific transcriptional signatures.

BACKGROUND Primary angle-closure glaucoma (PACG) damages retinal ganglion cells (RGCs) and is associated with neurodegeneration. This study used resting-state functional magnetic resonance imaging (fMRI) to analyze hemispheric lateralization and cooperative functional alterations in PACG. Machine learning assessed the...

Jing-Wen Qiu, Yuan-Zhi He, Si-Xian Li et al. · Neuroscience · 0 citations

Open access Aug 2026

Genetic architecture of treatment-resistant schizophrenia across East Asian and European cohorts: insights from GWAS, TWAS, and synaptic pathway analyses

There is promise in pathway-level and multi-omics approaches to elucidate biologically meaningful heterogeneity within SSD and support for synaptic mechanisms as potential targets for understanding and stratifying treatment-resistance is provided.

P. B. Leung, K. C. Wong, S. Smart et al. · medRxiv · 0 citations

Open access Aug 2026

A software package for simple and rigorous survival machine learning analysis in biomedical research

Survival analysis is a fundamental technique in biomedical research for modeling time-to-event data. It enables the identification of prognostic factors in disease, compares survival outcomes across treatment groups, and performs targeted treatment selection. A variety of machine learning (ML) approaches to survival an...

A. Pybus, J. Qiu, P. C. Morais Lyra et al. · medRxiv · 0 citations