Jing-Wen Wang

Multifunctional Nanoreactor Based on Catalyst Surface Engineering Combines pH-Adaptive Catalysis With Tumor Microenvironment Modulation for Synergistic Chemodynamic-Chemotherapy.

Chemodynamic therapy (CDT) is a novel therapeutic strategy based on the Fenton reaction, which utilizes endogenous hydrogen peroxide (H2O2) to generate toxic hydroxyl radicals (•OH) for killing tumor cells. However, the mildly acidic pH and limited H2O2 levels in the tumor microenvironment (TME) restrict the activity o...