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Oct 2026

M6A-Mediated Molecular Subtypes and Immune Microenvironment Remodeling in Colorectal Pathogenesis

Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, largely attributable to limitations in early detection and patient stratification. Although N6-methyladenosine (m6A) modification has emerged as a critical epitranscriptomic regulator in cancer biology, its role in driving molecular h...

Yan Cao, Shan He, Xue Xue et al. · 0 citations
Open access Sep 2026

FBP1‐Mediated Compartmentalization of Glycolytic Enzyme Complexes Suppresses PKM2 Function to Ameliorate MASLD Progression

It is shown that FBP1 is consistently downregulated during MASLD progression, with a progressive decline from MASL to MASH in clinical specimens and key preclinical models, and the FBP1‐PKM2 interaction is identified as a novel candidate intervention target for MASLD.

Bu-Song Wang, Yi-Ping Tang, Na Li et al. · 0 citations

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