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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Jing Xu

h-index 35 View on Semantic Scholar

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Open access Sep 2026

Targeting the PD-L1-induced PDK4/GLS metabolic axis overcomes anti-PD-1 resistance in non-small cell lung cancer

This study identifies a novel ‘PD-L1–ER stress–pyruvate–macrophage senescence’ axis as a key mechanism underlying primary resistance to ICB and proposes that targeting the PDK4/GLS-dependent pyruvate surge offers a promising therapeutic strategy to sensitize tumors to anti-PD-1 immunotherapy.

Wen-Xin Lian, Hui Yang, Yu-Qi Zhang et al. · 0 citations
Jul 2026

Functional noncoding variants within the TBX1 enhancer contribute to tetralogy of Fallot.

This study demonstrates the involvement of noncoding variants in the TBX1 enhancer in TOF pathogenesis, highlighting the feasibility of using organoids to decipher the underlying mechanisms of unconserved noncoding regions in developmental malformations.

Jimiao Gao, T. Jiang, Yingyi Quan et al. · 0 citations

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