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Author

Jing Xue

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Open access Oct 2026

Diverse patterns of transcriptional regulation and epigenetic reprogramming within PMDs contribute to ESCC progression by regulating EMT and immunosuppression

ABSTRACT Partially methylated domains (PMDs) represent extensive genome-wide hypomethylated regions that drive genomic instability and proto-oncogene activation. However, their complex regulatory influence on tumor-specific transcriptional networks remains largely elusive. In this study, we developed a robust computati...

Yan Huang, Jing Xue, Xue Luan et al. · 0 citations
Open access Aug 2026

Integrated metabolomics and mass spectrometry imaging reveal the Anti-Alzheimer’s mechanisms of turmeric and curcumin

Introduction Turmeric and its major bioactive component, curcumin, have shown promising potential in the prevention and management of Alzheimer’s disease (AD). However, the underlying molecular mechanisms and the contribution of turmeric residues remain incompletely understood. This study aimed to investigate the prote...

Ze-Min Yang, Yang-Yang Zeng, Jiahu Deng et al. · 0 citations

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