Jing-Ya Li

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

Metabolic reprogramming is a hallmark of many human diseases, including cancer, metabolic dysfunction, cardiovascular disease, and chronic inflammation. By reshaping bioenergetic and biosynthetic pathways, cells adapt to environmental stress and altered functional demands. Acetyl‐coenzyme A (acetyl‐CoA) plays a pivot...