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Open access Oct 2026

A cuproptosis-related gene signature centered on PDHB for prognostication and characterizing the immune microenvironment in uveal melanoma

Uveal melanoma (UM) is a highly metastatic intraocular malignancy with limited therapeutic options. The role of cuproptosis, a novel copper-dependent form of cell death, and its key regulator PDHB, in UM, remains completely unexplored. This study aims to construct a cuproptosis-related prognostic model and explor...

Ruo-Nan Ma, Zheng-Zheng Wu, Jing Yan et al. · 0 citations
Open access Aug 2026

LC-MS-based metabolomics reveals the In Vivo effects of cognitive formula 1 in rats with Aβ-induced Alzheimer’s disease

Results indicated that synergistic interactions among multiple CF1 components influence host metabolic pathways, in particular those involved in glycerophospholipid and amino acid metabolism, thereby suggesting an explanation for the alleviation of systemic metabolic dysregulation by the formulation.

Di Wu, Yanling Lin, Wenjun Guo et al. · 0 citations

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