Author

Jing-Yan Liang

3 papers indexed here

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Open access Sep 2026

Hypertriglyceridemia and atherosclerosis in Apolipoprotein A5 mutant rabbits generated using CRISPR/Cas9.

ApolipoproteinA5 (APOA5) plays an important role in regulating plasma triglycerides (TG). Most in vivo data, however, derive from murine models whose lipoprotein metabolism diverges substantially from humans, and no rabbit APOA5 loss-of-function model has previously been described. Microinjection of Cas9 mRNA and two e...

Yi-Wen Zha, Lin-Ling Feng, Ting Zhang et al. · Journal of Lipid Research · 0 citations

Review Sep 2026

Microplastics and Nanoplastics: Potential Implications for Testicular Inflammation in Male Mammals.

Current evidence on human exposure, systemic distribution, and the testicular fate of MNPs is summarized, and their effects on germ cells, Sertoli cells, Leydig cells, and resident immune cells are critically evaluated to clarify the reproductive consequences of MNP exposure.

Fan Du, Bo-Wen Xue, Yu-Ming He et al. · Reproductive Toxicology · 0 citations

Sep 2026

Embryonic Dibutyl Phthalate Exposure Disrupts Sertoli Cell Glycolipid Metabolism to Drive Premature Spermatogenesis in PND 22 Male Offspring: A Role for the AMPK/Autophagy Axis.

Dibutyl phthalate (DBP), a widely used plasticizer, is frequently added to various plastic products. Being a prevalent environmental endocrine disruptor, DBP interacts non-covalently with plastic matrices, which promotes its release into surrounding environments and subsequent risks to human health. Our previous studie...

Tan Ma, Cheng-Hao Shen, Liang Kong et al. · Toxicology · 0 citations