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Review Sep 2026

Multifunctional platinum(IV) prodrugs: Targeted delivery, stimuli-responsive release, and precision oncology.

Platinum-based chemotherapy remains the cornerstone of cancer treatment, but it faces inherent limitations such as dose-limiting toxicity, acquired resistance, and poor tumor specificity. Platinum(IV) prodrugs, with their octahedral configuration and two modifiable axial sites, have evolved into multifunctional platfor...

Yu-Ming Chen, Peng-Min Shi, Bo Yang et al. · 0 citations

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