Author

J. Li

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Open access Sep 2026

A six-metabolite signature characterizes metabolically unhealthy obesity and reveals hidden metabolic risk within metabolically healthy obesity

Background/objectives Metabolically healthy obesity (MHO) is commonly defined by the absence of metabolic syndrome-related abnormalities despite obesity. However, conventional clinical definitions may overlook substantial metabolic heterogeneity and hidden cardiometabolic risk. We aimed to identify metabolomic signatur...

Pan Gao, Mei-Fang Liang, Bin-Feng Tang et al. · Frontiers in Endocrinology · 0 citations

Open access Aug 2026

Meal timing entrains circadian rhythms in the dorsal vagal complex, a brainstem satiety centre

The dorsal vagal complex (DVC) includes a multi-component brainstem satiety centre which has gained attention as a key target of anti-obesity pharmacotherapies. Our recent studies revealed its circadian timekeeping properties, with molecular and electrophysiological 24 h rhythms persisting independently of the primary...

L. Chrobok, Charlotte Muir, T. Kaur et al. · PLoS Biology · 0 citations